The strength of CAST is in its multivalent approach to support cancer treatment.

First it inhibits the activity of the P-gp pumps. Knocking down this resistance mechanism maintains the chemotherapeutic agents within the tumor cells where they can fully express their anti-tumor action. This ensures that every tumor cells receives its due dose of chemotherapeutic agents regardless of how many P-gp pumps it may express. Making all tumor cells equals in the face of chemotherapy may further prevent the appearance of chemotherapy resistance.

Second, inhibiting the proteolytic activity of MMP-2 on the collagen matrix prevents the switch to a more invasive type of cancer. Maintaining the cancer cells sensitivity to therapeutic agents and preventing the growth of tumors and the development of metastasis shall greatly improve the overall rate of survival among cancer patients under a chemotherapeutic regimen.

CAST may be useful for subjects who wish to optimize a chemotherapeutic treatment of cancer (consult your health care professional).